To determine whether disease and training status results in different recovery kinetics of gas exchange and heart rate response in elderly subjects, 12 healthy control subjects, 18 patients with chronic obstructive pulmonary disease and 12 master athletes were examined during the five-minute recovery from maximal graded exercise. The recovery rate constants of oxygen uptake (VO2), carbon dioxide production (VCO2), ventilation (VE), and heart rate (HR) were fitted by a one-exponential model. Nonlinear regression showed that COPD exhibited a significantly slower recovery decay than CS for (VO2), (VCO2) and (VE), whereas HR recovery appeared to be unaffected by the disease status compared to controls. MA recovered faster than CS, except for (VE) recovery decay. We also demonstrated that the gas exchange and heart rate recovery kinetics were independent of maximal exercise work rate. We conclude that training generally improved the recovery responses in elderly subjects in contrast to the status of respiratory disease


oxygen uptake ; carbon dioxide production ; heart rate ; ventilation ; recovery ; elderly subjects

Texte intégral :



- Wasserman K. and Casaburi R., "Acid-base regulation during exercise in humans. In Exercise", Edited by Whipp B J. and Wasserman K., New York, Marcel Dekker (1991), pp. 405-448.

- Hagberg J.M., King D.S., Rogers M.A., Montain S.J., Jilka S.M., Kohrt W.M., Heller S.L., "Exercise and recovery ventilatory and VO2 responses of patients with MCArdle's disease", J. Appl. Physiol., 68, (1990), pp.1393-1398.

- Riley M., Stanford C.F. and Nicholls D.P., "Ventilatory and heart rate responses after exercise in chronic cardiac failure", Clin. Sci., 87, (1994), pp.231-238.

- Harris, R.R., Edwards R., Hultman E., Nordesjِ L.O., Nyland B., Sahlin K., "The time course of phosphorylcreatine resynthesis during recovery of the quadriceps muscle in man", Pƒlügers Arch, 367, (1976), pp.137-142

- Gertz I., Hedenstierna G., Hellers G., Wahren J., "Muscle metabolism in patients with chronic obstructive lung disease and acute respiratory failure failure", Clin. Sci. Molecular Med., 52, (1977), pp.395-403.

- Coggan A.R., Abduljalil A.M., Swansson S.C., Earle M.S., Farris J.W., Mendenhall L.A., Robitaille P.M., "Muscle metabolism during exercise in young and older untrained and endurance trained men", J. Appl. physiol., 75, (1993), pp.2125-2133.

- Casaburi R., Petty T.L., "Principles and Practice of Pulmonary Rehabilitation", Edited by Casaburi R. and Petty T.L., WB Saunders Company, a division of Harcourt Brace & Company, Philadelphia, (1993).

- Préfaut C., Varray A., Vallet G., "Pathophysiological basis of exercise training in patients with chronic obstructive lung disease", Eur. Resp. Rev., 5, (1995), pp.27-32.

- Chick T.W., Cagle T.G., Vegas F.A., Poliner J.K., Murata G.H., "Recovery of gas exchange variables and heart rate after maximal exercise in COPD", Chest, 97, (1990), pp.276-279.

- Préfaut C., Anselme F., Caillaud C., Massé-Biron J., "Exercise-induced hypoxemia in older athletes", J. Appl. Physiol., 76, (1994), pp.120-126.

- Darr K., Basset D.R., Morgan B.J., and Thomas D.P., "Effects of age and training status on heart rate recovery after peak exercise", Am. J. Physiol., 254, (1988), pp.H340-H343.

- Cohen-Solal A., Laperche T., Morvan D., Geneves M., Caviezel B., Gourgan R., "Prolonged kinetics of recovery of oxygen consumption after maximal graded exercise in patients with chronic heart failure", Circulation, 91, (1995), pp.2924-2932.

- Standards for diagnosis and care of patients with chronic obstructive pulmonary disease, Resp. Crit. Car. Med., 5, (1995), pp.S77-S121.

- Sorbini C.A., Grassi V., Solinas E., Muiesan G., "Arterial oxygen tension in relation to age in healthy subjects", Respiration, 25, (1968), pp.3-13.

- Zanconato S., Cooper D.M., Armon Y., "Oxygen cost and oxygen uptake dynamics and recovery with 1 min of exercise in children and adults", J. Appl. Physiol., 71, (1991), pp.993-998.

- Bland J.M., Altman D.G., "Statistical methods for assessing agreement between two methods of clinical measurement", The Lancet, 8, (1986), pp.307-310.

- Hagberg J.M., Hickson R.C., Ehsani A.A. and Holloszy J.O., "Faster adjustment to and recovery from submaximal exercise in the trained state", J. Appl. Physiol., 48, (1980), pp.218-224.

- Jakobsson P., Jorfeldt L., Henriksson J., "Metabolic enzyme activity in the quadriceps femoris muscle in patients with severe chronic obstructive pulmonary disease", Am. J. Respir. Crit. Care Med., 151, (1995), pp.374-377.

- Coggan A.R., Spina R.J., Rogers M.A., King D.S., Brown M., Nemeth P.M., Holloszy J.O., "Histochemical and enzymatic characteristics of skeletal muscle in master athletes", J. Appl. Physiol., 68, (1990), pp.1896-1901.

- Proctor D.N., Sinning W.E., Warlo J.M., Sieck G.C., Lemon W.R., "Oxidative capacity of human muscle fiber types: effects of age and training status", J. Appl. Physiol., 78, (1995), pp.2033-2038.

- McCully K.K., Boden B.P., Tuchler M., Fountain M.R., Chance B. "Wrist flexor muscles of elite rowers measured with magnetic resonance spectroscopy", J. Appl. Physiol., 67, (1989), pp.926-932.

- McCully K., Strear C., Prammer M., Leigh J., Dept Jr., "Post-exercise recovery of phosphocreatine as an index of oxidative capacity", Faseb, J 4, (1990), pp. A1221.

- Casaburi R., Whipp B.J., Wasserman K., Beaver W.L., Koyal S.N., "Ventilatory and gas exchange dynamics in response to sinusoidal work", J. Appl. Physiol. 42, (1977), pp.300-311.

- Poehlman E.T., Gardner A.W., Arciero P.J., Goran M.I., Calles-Escandon J., "Effects of endurance training on total fat oxidation in elderly persons", J. Appl. Physiol., 76, (1994), pp.2281-2287.

- Whipp B.J. and Ward S.A., In "Exercise", Edited by Whipp BJ and Wasserman K. New York, Marcel Dekker, (1991), pp.405-448

- Brooks G., "Increased glucose dependency in circulatory compensated hypoxia. In Sutton J, Coates G and Houston C, editors Advances in biosciences: hypoxia and mountain medecine", Vol 84. New York: Pergamon Press, (1992), pp.213-226.

- Furlan R., Piazza S., Dell'Orto S., Gentile E., Cerutti S., Pagani M. and Malliani A., "Early and late effects of exercise and athletic training on neural mechanisms controlling heart rate", Cardiovascular Research, 27, 3, (1993), pp.482-488.

- Child J.S., Barnard R.J., Taw R.L., "Cardiac hypertrophy and function in master endurance runners and sprinters", J. Appl. Physiol., 57, (1984), pp.176-181.

- Baraldi E., Cooper D.M., Zanconato S. and Armon Y., "Heart rate recovery from 1 minute of exercise in children and adults", Pediatr. Res., 29, (1991), pp.57


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