MISE AU POINT D'UN MODELE EXPERIMENTAL D'ASPERGILLOSE PULMONAIRE CHEZ LA SOURIS
Mots-clés :
Aspergillus fumigatus, Aspergillose pulmonaire, SourisRésumé
Aspergillus fumigatus est le principal agent causal des aspergilloses humaines dont la forme la plus grave est l'aspergillose pulmonaire invasive très fréquente chez des sujets fortement imunodéprimés, Nous avons donc tenté de mettre au point un modèle expérimental d'aspergillose pulmonaire invasive chez la souris se rapprochant le plus des conditions naturelles d'infestation, ce qui nous permettra d'étudier le développement in vivo de ce champignon. Le modèle expérimental que nous avons mis au point est réalisé par dépôt d'une suspension de spores sur les narines de l'animal immunodéprimé par administration quotidienne d'acétate de cortisone.Téléchargements
Références
- Bhatia V.N. and Mohapatra L.N., "Experimental aspergillosis in mice. Part I. Pathogenic potentiel of Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger", Mykosen., 12, (1969), pp. 651-654.
- Bhatia V.N. and Mohapatra L.N., "Experimental aspergillosis in mice. Part II. Enhanced susceptibility of cortisone treated mice to infection with Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger, Mykosen., 13, (1970), pp. 105- 110.
- Bodey G.P. and Vartivarian S., "Aspergillosis", Eur. J. Clin. Microbiol. Infect. Dis., 8, (1989), pp. 413-437.
- Bouchara J P., Larcher G., Joubaud F., Penn P., Tronchin G. and Chabasse D., "Extracellular fibrinogenolytic enzyme of Aspergillus fumigatus : substrate-dependent variations in the proteinase synthesis and characterization of the enzyme", FEMS Immunol. Med. Microbiol., 7, (1993), pp.81-92.
- Cimon B., Carrere J., Chazalette J.P., Ginies J.L., Chabasse D., et Bouchara J.P., "Mycoses broncho-pulmonaires au cours de la mucoviscidose. Résultats d'une étude épidémiologique longitudinale sur une période de 5 ans", J. Mycol. Méd., 10, (2000), pp. 128-135.
- Denning D.W., Ward P.N, Fenelon L.E. and Benbow E.W., "Lack of vessel wall elastolysis in human invasive pulmonary aspergillosis", Infect. Immun., 60, (1992), pp. 5153-5156.
- Dixon D.M., Polak A. and Walsh T.J., "Fungus dose-dependent primary pulrnonary aspergillosis in immosupressed mice", Infect. Immun., 57, (1989), pp.452-1456.
- Eisenstein D.J., Binddinger P.W. and Rhodes J.C., "Experimental murine invasive pulmonarv aspergillosis", Am. J. Clin. Path., 93, (1990), pp.510-515.
- Epstein S.M., Verney E., Miale T.D. and Sidransky H., "Studies on the pathogenesis of experimental pulmonary aspergillosis", Amer. J. Pathol., 51, (1967), pp.769-788.
- Ford S. and Friedman L., "Experimental study of the pathogenicity of Aspergilli for mice", J. Bacteriol., 94, (1967), pp. 928-933
- Graybill J.R., and Kaster S.R., "Experimental murine aspergillosis. Comparison of arnphotericin B and a new polyene antifungal drug SCH 28193", Am. Rev. Respir. Dis., 129, (1984), pp.292-295.
- Graybill J.R., Kaster S.R. and Drutz D.J., "Treatment of experimental murine aspergillosis with BAY n° 7133", J. Infect. Dis., 148, (1983), pp.898-906.
- Hector R.F., Yee E. and Collins M.S., "Use of DBA/2N mice in models of systemic candidiasis and pulmonary and systemic aspergillosis", Infect. Immun., 58, (1990), pp.1476-1478.
- Kolattukudy P.E., Lee J.D., Rogers L.M., Zimmerman P., Ceselski S., Fox B., Stein B. and Copelan E.A., "Evidence for possible involvement of an elastolitic serine protease in aspergillosis", Infect. Immun., 61, (1993), pp.2357-2368.
- Kothary M.H., Chase T.Jr. and Mc. Millan J.D., "Correlalion of elastase production by some strains of Aspergillus fumigatus with abitilty to cause pulmonary invasive aspergillosis in mice", Infect. Immun., 43, (1984), pp. 320-325.
- Kurup V.P. and Sheth N.K., "Experimental aspergillosis in rabbits", Comp. Immunol. Microbiol. Infect. Dis., 4, (1981), pp. 161-174.
- Land C.J.. Sostaric B., Fuchs R., Lundstrom H. and Hult K., "Intratracheal exposure of rats to Aspergillus fumigatus spores isolated from sawmills in Sweden", Appl. Environ. Microbiol., 55, (1989), pp.2856-2860.
- Larcher G., Bouchara J.P.. V. Annaix, F. Symoens, D. Chabasse and G. Tronchin, "Purification and characterization of a fibrinogenolytic serine proteinase from Aspergillus fumigatus culture filtrate", FEBS Lett., 308, (1992), pp.65-69.
- Lehmann P.F., and White E.O., "Chitin assay used to demonstrade renal localisation and cortisone-enhanced growth of Aspergillus fumigatus mycelium in mice", Infect. Immun., 12, (1975), pp.987-992.
- Merkow L.P., Epstein S.M., Sidransky H., Verney E. and Pardo M., "The pathogenesis of experimental pulmonary aspergillosis. An ultrastuctural study of alveolar macrophages after phagocytosis of Aspergillus flavus spores in vivo", Am. J. Pathol., 69, (1971), pp.57-74.
- Miyaji M., and Nishimura K., "Relationship between proteolytic activity of Aspergillus fumigatus and the fungus invasiveness of mouse brain", Mycopathologia, 62, (1977), pp.561-666.
- Monod M., Paris S., Sarfati J., Jaton-Ogay K., Ave P. and Latgé J.P., "Virulence of alkaline protease-deficient mutants of Aspergillus fumigatus", FFMS. Microbiol. Lett., 106, (1993), pp.39-46.
- Niki Y., Bernard E.M., Edwards F.F., Schmitt H.J., Yu B. and Amstrong D., "Model of recurrent pulmonary aspergillosis in rats", J. Clin. Microbiol., 29, (1991), pp.1317-1322.
- Olenchock S.A., Green F.H.Y., Mentnech M.S., Mull J.C. and Sorenson W.G., "In vivo pulmonary response to Aspergillus terreus spores" Comp. Immunol. Microbiol. Infect. Dis., 6, (I983), pp.67-80.
- Rippon J.W. and Anderson D.N., "Experimental mycosis in immunosuppressed rabbits- II. Acute and chronic aspergillosis", Mycopathologia, 64, (1978), pp.97-100.
- Rondle C.J. and Morgan W.T.J., "Determination of glucosamine and galactosamine", Biochein. J., 61, (1955), pp. 586-589.
- Sandhu D.K., Sandhu R.S., Damodaran V.N. and Randhawa H.S., "Effect of cortisone on bronchopulmonary aspergillosis in mice exposed to spores of various Aspergillus specie", Sabouraudia, 8, (1970), pp. 32-38.
- Schaffner A., Douglas H., and Braude A., "Selective protection against conidia by mononuclear and against mycelia by polymorphonuclear phagocytes in resistance to aspergillosis. Observations on these two lines of defense in vivo and in vitro with human and mouse phagocvtes", J. Clin. Invest, 69, (1982), pp. 631-657.
- Schmitt H.J., Bernard E.M., Edwards F.F. and Armstrong D., "Combination therapv in a model of pulmonary aspergillosis", Mycoses, 34, (1991), pp. 281-285.
- Schmitt H.J., Bernard E.M., Hauser M. and Armstrong D., "Aerosol amphotericin B is effective for prophylaxis and therapy in a rat model of pulmonary aspergillosis", Antimicrob. Agents Chemother., 32, (1988), pp. 1676-1679.
- Schmitt H.J, Edwards F., Andrade J., Niki Y. and Armstrong D., "Comparison of azoles against aspergilli in vitro and in an experimental model of pulmonary aspergillosis", Chemotherapy, 38, (1992), pp.118-126.
- Shibuya K., Takaoka M., Uchida K., Wakayama M., Yamaguchi H., Takahashi K., Paris S., Latgé J.P., and Naoe S., "Histopathology of experimental invasive pulmonary aspergillosis in rats : pathological comparison of pulmonary lesions induced by specific virulent factor deficient mutants", Microb. Pathog., 27, (1999), pp.123-131.
- Sidransky H. and Friedman E., "The effect of cortisone and antibiotic agents on experimental pulmonary aspergillosis", Am. J. Pathol., 35, (1959), pp.169-184.
- Sidransky H. and Verney E., "Experimental aspergillosis", Lab. Invest., 11, (1962), pp. 1972-1183.
- Sidransky H., Verney E. and Beed H., "Experimental pulmonary aspergillosis", Arch. Pathol., 79, (1965), pp.299-309.
- Spreadbury C.I., Krausz T., Pervez S. and Cohen J., "Invasive aspergillosis : clinical and pathological features of a new animal model", J. Med. Vet. Mycol., 27, (1989), pp. 5-15.
- Turner K.L, Hackashaw R., Papadimitrou J. and Perrot J., "The pathogenesis of experimental pulmonary aspergillosis in normal and cortisone-treated rats", J. Pathol. 118, (1975), pp. 65-73.
- Waldorf A.R., Lavitz S.M. and Diamond R.D., "In vivo bronchoalveolar macrophage defense against Rhizopus oryzae and Aspergillus fumigatus". J. Infect. Dis., 150, (1984), pp.752 -760.
- Walzl H.L., Ackerbauer H., Meingassner J.G. and Mieth H., "Histopathology of organ lesions in mice after an intravenous or intratracheal or intrarenal infection with Aspergillus fumigatus", Mykosen, 30, (1986), pp. 10-18
- White L.O., "Germination of Aspergillus fumigatus conidia in the lungs of normal and cortisone-treated mice", Sabourandia., 15, (1977), pp. 37-41.
