REPONSES METABOLIQUES ET ENDOCRINIENNES (INSULINEMIE ET PROLACTINEMIE) A UN STRESS CHRONIQUE A L’ETHER CHEZ LE RAT MALE NORMAL ET DIABETIQUE
Mots-clés :
Streptozotocin, ether, metabolism, insulin, ratRésumé
Ce travail contribue à la mise en évidence d’interrelations entre le système neuroendocrinien et le système immunitaire chez un modèle diabétique soumis à un stress chronique cognitif à l’éther.
Les résultats révèlent l’effet de différents traitements sur les métabolismes glucidiques, lipidiques et sur le système de détoxification. En effet, l’administration de la streptozotocine a induit un diabète, révélé par une hyperglycémie durable associée à une augmentation significative des triglycérides, du cholestérol et d’une diminution du glutathion réduit. L’addition du stress montre une altération de la riposte des sujets diabétiques en comparaison avec les normo-glycémiques, au niveau métabolique et endocrinienRéférences
- Dantzer R., Kelly K.W., "Stress and immunity, an integrated view of relation ship between the brain and immune system", Life Sce., 44, (1983), pp.1995-2008.
- Geullati M.A., "Les relations immuno-corticotropes, effets de la bursectomie embryonnaire et du traitement substitutif par la bursine", Thése de doctorat. Univ. Montapellier II, (1991).
- Guellati M.A., Bayle J.D., Roux J., "Brucella abortus antigen stimulates the pituitary-adrenal axis through the extrapituitary B lymphoid system", Pog. Immun. Neuroendocrinology, 4, (1991), pp.99-102.
- Surwit R.S., Schneider M.S., Feinglos M.N., "Stress and Diabetes Mellitus", Diabetes Care, 15, 10, (1992), pp.1413-1422.
- Robinovitch A., "Roles of cytokines in IDDM pathogenesis and islet β-cell destruction", Diabetes reviews, 2, (1993), pp.215-233.
- Yogev L., Yavetz H., Gottriech A., Oppenhiem D., Homonnai Z.T., Paz G., "Serum prolactin response to ether stress in diabetic rats: Opiate system contribution", Life Sci., 148, 9, (1991), pp.887-891.
- Scribner K.A., Akana S.F., Walker C.D., Dallman N.F., "Streptozotocin - diabetic rats exhibit facilitated adrenocorticotropin responses to acute stress, but normal sensitivity to feed back by corticosteroids", Endocrinology, 133, 6, (1992), pp.2667-2674.
- Holstad M., Sandler S., "Prolactin protect against diabetes induced by multiple low doses of streptozotocin in mice", Endocrinology, 163, (1999), pp.229-234.
- Zhu X.H., Zellwerger R., Wichmann M.W., Ayala A., Chaudry ICH., "Effect of prolactin and metoclopramide on macrophage cytokine gene expression in late sepsis", Cytokine, 9, (1997), pp.437-446.
- Herr E., Bergy M.E., Jahnke H.K., "Isolation and characterization of streptozotocin", Antibiotics Annu., 7, (1959), pp.326-240.
- Fokumoto H., Seimos S., Imura H., Seino Y., Eddy R.L., Fukushima Y., Byers M.G., Shows I.B., Bell G.I., "Sequence, tissue distribution and chromosomal localization of MRNA encoding a human glucose transporter-like protein", Proc. Nat. Acad. Sci., 85, (1988), pp.5434-5438.
- Okamoto H., " Regulation of proinsulin synthesis in pancreatic islets and a now aspect to insulin- dependent diabetes", Mol. Cell Biochem., 37, (1981), pp.323-328.
- Ramade F. Bouille G., Bayle J.D., "Adronocortical response in chronically catheterized thalamic pigeons", Neuroendocrinology, 30, (1982), pp.323-328.
- Trinder L., "Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor", Ann. Clin. Biochem., 6, (1969), pp.24-28.
- Thomas et Labor, "Colorimetric method for biological analysis", Lab. Diag., 4, (1992), pp.99-115.
- You J.S., Chang K.J., "Effect of taurine supplementation on lipid peroxidation, blood glucose and blood lipid metabolism in streptozocin-induced diabetic rats", Adv. Exp. Med. Biol., 42, (1998), pp.163-168.
- Kujlin B., Rjasnowski I., Gries F.A., Kold H., "Antibodies to proinsulin and insulin as predictive markers of type 1 diabetes", Diabetic Med., 7, (1990), pp.310-314.
- Weckbeker G., Coy Y.G., "Ribonucleotide reductase activity and growth of glutathione depleted mouse", Leukimia L., 40, (1976), pp.257-264.
- Willis T., "Pharmaceutice rationalis or an excitation of thoperations of medecine in human bodies", In The Works of Thomas Willis. London: Dring, Harper, Leigh, (1679).
- Carter, WR., Herman J., Stokes K., Cox D.J., "Promotion of diabetes onset by stress in BB rat", Diabetologia, 30, (1987), pp.674-675.
- Cannon W.B., "Bodily changes in pain, hunger, fear and rage", New York., MacMillan, (1941).
- Robinson N., Fuller J.H., "Role of life events and difficulties in the onset of diabetes mellitus", J. Psychosom. Res., 29, (1985), pp.583-591.
- Robinson N., Lioyd C., Fuller J.H., Yateman N., "Psychosocial factors and the onset of type 1 diabetes", Diabetic Med., 6, (1988), pp.53-58.
- Vialletes B., Ozanon J.P., Kaplansky S., Farnarier C., Sauvaget E., Lassman-Vague V., Vague P., "Stress antecedents and immune status in recently diagnose type1 insulin-dependent diabetes mellitus", Diabetes Metab., 15, (1989), pp.45-50
- Thernlund M.G., Dahlquist G., Hansson K. Ivarsson S.A., "Psychological Stress and the onset of IDDM in children a case control study", Diabetes Care, 18, 10, (1995), pp.1323-1329.
- Bellush L., Rowland N.E., "Stress and behavior in streptozotocin diabetic rats: biochemical correlates of passive learning", Behav Neurosci., 103, (1989), pp.144-150.
- Chase H.P., Jackson G.G., "Stress and sugar control in children with IDDM", J. Pediatr., 98, (1981), pp.1011-1013.
- Viner R., Mcgrath M., Trudinger P., "Family stress and metabolic control in diabetes", Arch. Dis. Child., 74, 5, (1996), pp.418-421.
- Shimazu T., "Central nervous system regulation of liver and adipose tissue metabolism", Diabetologica, 20, (1999), pp.343-366.
- Nonogaki K., Iguchi A., "Stress acute hyperglycaemia and hyperlipidimia, role of the autonomic nervous system and cytokines", Elesevier Sciences Inc., 5, (1997), pp.192-195
- Weinberger M.H., "Antihypertensive therapy and lipids evidence mechanisms and implications", Arch. Intern. Med., 145, (1985), pp.1102-1105.
- Thierry V., "Physiologie du tissu adipeux", Physiol., 57, (2001), pp.55-65.
- Chicouri M.J., "Diabète", MA. Edition Paris, (1983), pp.195-200.
- Gala R.R., "Prolactin and growth hormone in the regulation of the immune system", Proceedings of the Society for Experimental Biology and Medicine, 198, (1991), pp.513-527.
- Ratner A., Pasternack L.B., Weiss G.K., "Effect of restraint stress on prolactin and corticosterone levels in streptozotocin-induced diabetic rats", Life Science, 54, 4, (1994), pp.261-266.