ASSESSMENT OF FOLATE STATUS: MEASUREMENT OF HOMOCYSTEINE versus VITAMIN B12 AND FOLATE

Auteurs-es

  • B HOUCHER Laboratoire de Physiologie Cellulaire Département de Biologie Faculté des Sciences Université de Sétif Sétif 19000, Algérie
  • M CANDITO Laboratoire de Biochimie Hôpital Pasteur 30 Avenue de la Voie Romaine B.P. 69, 06002-Nice Cedex 1, France
  • S NECIB Laboratoire de Biologie- Physiologie Cellulaire Département de Biologie Faculté des Sciences Université Mentouri Constantine, Algérie
  • D NAIMI Laboratoire de Biologie- Physiologie Cellulaire Département de Biologie Faculté des Sciences Université Mentouri Constantine, Algérie
  • S BEGAG Laboratoire de Physiologie Cellulaire Département de Biologie Faculté des Sciences Université de Sétif Sétif 19000, Algérie

Mots-clés :

acide folique, vitamine B12, vitamine B6, homocystéine, statut folate, questionnaire alimentaire folate

Résumé

There was no statistically significant difference between controls and patients for dietary folate. Also the plasma folate level did not slightly differ between the controls and patients. Patients had higher average homocysteine concentrations than control subjects (p<0.05). A significant relationship was observed in controls between plasma folate concentrations and the homocysteine levels (p=0.01), and the folate questionnaire (p=0.001). We found in controls significant positive correlation between vitamin B12 and vitamin B6 (p=0.05). In patients, vitamin B12 is inversely associated with homocysteine (p=0.05). 

Bibliographies de l'auteur-e

B HOUCHER, Laboratoire de Physiologie Cellulaire Département de Biologie Faculté des Sciences Université de Sétif Sétif 19000, Algérie

Laboratoire de Physiologie Cellulaire

Département de Biologie

Faculté des Sciences

M CANDITO, Laboratoire de Biochimie Hôpital Pasteur 30 Avenue de la Voie Romaine B.P. 69, 06002-Nice Cedex 1, France

Laboratoire de Biochimie

Hôpital Pasteur

S NECIB, Laboratoire de Biologie- Physiologie Cellulaire Département de Biologie Faculté des Sciences Université Mentouri Constantine, Algérie

Laboratoire de Biologie-

Physiologie Cellulaire

Département de Biologie

Faculté des Sciences

D NAIMI, Laboratoire de Biologie- Physiologie Cellulaire Département de Biologie Faculté des Sciences Université Mentouri Constantine, Algérie

Laboratoire de Biologie-

Physiologie Cellulaire

Département de Biologie

Faculté des Sciences

S BEGAG, Laboratoire de Physiologie Cellulaire Département de Biologie Faculté des Sciences Université de Sétif Sétif 19000, Algérie

Laboratoire de Physiologie Cellulaire

Département de Biologie

Faculté des Sciences

 

 

Références

- Dawson D.W., Waters H.M., "Malnutrition: Folate and cobalamin deficiency", Br. J. Biomed. Sc., 51, (1994), pp.221-227.

- National Research Council. Recommended Dietary Allowances, 10th ed. Washington, D.C., National Academy Press, (1989), pp. 158-165.

- Poitier de Courcy G., "Apports nutritionnels conseillés en folates", An. Biol. Clin., 59, (2001), pp.198-209.

- Colman N., Herbert V., "Dietary assessments with special emphasis on prevention of folate deficiency", In: M. I. Botez and E.H. Reynolds, eds. Folic acid in Neurology, Psychiatry, and Internal Medicine. Raven press, New York, (1979), pp. 23-33.

- Herbert V., "Vitamin B12", In: Nutrition Reviews, Present Knowledge in Nutrition, 5th ed. The Nutrition Foundation, Washington, D.C., (1984), pp. 347-364.

- Pietrzik K., Bronstrup A., "Vitamins B12, B6 and folate as determinants of homocysteine concentration in the healthy population", Eur. J. Pediatr., 157, (1998), pp. S135-S138.

- Hultberg B., Isaksson A., Nilsson K., Gustafson L., "Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly", Int. J. Geriatr. Psychiatry, 16, (2001), pp. 873-878.

- Brunner E., Stallone D., Juneja M., Bingham S., Marmot M., "Dietary assessment in Whitehall II: comparison of 7 d diet diary and food-frequency questionnaire and validity against biomarkers", Br. J. Nutr., 86, (2001), pp. 405-414.

- Knutsen S.F., Fraser G.E., Linsted K.D., Beeson W.L., Shavlik D.J., "Comparing biological measurements of vitamin C, folate, alpha-tocopherol and carotene with 24-hour dietary recall information in nonhispanic blacks and whites", Ann. Epidemiol., 11, (2001), pp. 406-416.

- Department of health. Folic Acid and the Prevention of Disease. Report on Health and Social Subjects, 50. London: HMSO, (2000).

- Quinn K., Basu T.K., "Folate and vitamin B12 status of the elderly", Eur. J. Clin. Nutri., 50, (1996), pp.340-342.

- Alaimo K., Mc Dowell M.A., Briefel R.R. et al., "Dietary Intake of Vitamins, Minerals, and Fiber of Persons Ages 2 Months and Over in the United States: Third National Health and Nutrition Survey, Phase 1, 1988-91", National Center for Health Statistics. Advance Data N° 258, (1994).

- Malinow M.R., Duell P.B., Hess D.L., Anderson P.H., Kruger W.D., Phillipson B.E., Gluckman R.A., Block P.C., Upson B.M., "Reduction of plasma homocyst(e)ine levels by breakfast cereal fortified with folic acid in patients with coronary heart disease", New Engl. J. Med., 338, (1998), pp. 1009-1015.

- Jacques P.F., Sulsky S.I., Sadowski J.A., Phillips J.C., Rush D., Willett W.C., "Comparison of micronutrient intake measured by a dietary questionnaire and Biochemical indicators of micronutrient status", Am. J. Clin. Nutr., 57, (1993), pp. 182-189.

- Selhub J., Jacques P.F., Wilson P.W., Rush D., Rosenberg I.H., "Vitamin status and intake as primary determinants of homocysteinemia in an elderly population", JAMA, 270, (1993), pp. 2693-2694.

- van Guldener C., Robinson K., "Homocysteine and renal disease", Seminars in Thrombosis and Hemostasis, 26, (2000), pp. 313-324.

- Hughes K., Ong C.N., "Homocysteine, folate, vitamin B12, and cardiovascular risk in Indians, Malays, and Chinese in Singapore", J. Epidemiol. Community Health, 54, (2000), pp. 31-34.

- Brattstrom L.E., "Vitamins as homocysteine lowering agents", J. Nutr., 126, (1996), pp. 1276S-1280S.

- Marasini B., Casari S., Bestetti A., Maioli C., Cugno M., Zeni S., Turri O., Guagnellini E., Biondi M.L., "Homocysteine concentration in primary and systemic sclerosis associated Raynaud’s phenomenon", J. Rheumatol., 27, (2000), pp. 2621-2623.

- Bates C.J., Mansoor M.A., Gregory J., Pentieva K., Prentice A., "Correlates of plasma homocysteine, cysteine and cysteinyl-glycine in respondents in the British National Diet and Nutrition Survey of Young People Aged 4 -18 Years, and a comparison with the Survey of People Aged 65 Years and Over, Br. J. Nutr., 87, (2002), pp. 71-79.

- Fuchs D., Jaeger M., Widner B., Wirleitner B., Artner-Dworzak E., Leblhuber F., "Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?", Clin. Chem. Lab. Med., 39, (2001), pp. 691-694.

- Verhoef P., Stampfer M.J., Buring J.E., Gaziano J.M., Allen R.H., Stabler S., Reynolds R.D., Kok F.J., Hennekens C.H., Willett W.C., "Homocysteine metabolism and risk of myocardial infarction: Relation with vitamins B6, B12, and folate", Am. J. Epidemiol., 143, (1996), pp. 845-859.

- Kruger W.D., "Vitamins and homocysteine metabolism", Vitamins and Hormones, 60, (2001), pp. 333-352.

- Robinson K., Arheart K., Refsum H., Brattstrm L., Boers G., Ueland P., Rubba P., Palma-Reis R., Meleady R., Daly L., Witteman J., Graham I., "The European Comac Group. Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease", Circulation, 97, (1998), pp. 437-443

- Curtis D., Sparrow R., Brennan L., van der Weyden M., "Elevated serum homocysteine as a predictor for vitamin B12 or folate deficiency", Eur. J. Haematol., 52, (1994), pp. 227-232.

- Compher C.W., Kinosian B.P., Evans-Stoner N., Huzinec J., Buzby G.P., "Hyperhomocysteinemia is associated with venous thrombosis in patients with short Bowel syndrome", Journal of Parenteral and Enteral Nutrition, 25, (2001), pp. 1-8.

- Snow C.F., "Laboratory diagnosis of vitamin B12 and folate deficiency", Arch. Inter. Med., 159, (1999), pp. 1289-1298.

- Jacques P.F., Selhub J., Bostom A.G., Wilson P.W.F., Rosenberg I.H., "The effect of folic acid fortification on plasma folate and total homocysteine concentrations", N. Engl. J. Med., 340, (1999), pp. 1449-1454.

- Klee G.G., "Cobalamin and folate evaluation: Measurement of methylmalonic and homocysteine vs vitamin B12 and folate", Clin. Chem., 46, (2000), pp. 1277-1283.

- Ubbink J.B., Vermaak W.J.H., van der Merwe A., Becker P.J., "Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia", Am. J. Clin. Nutr., 57, (1993), pp. 47-53.

- van Guldener C., Stehouwer C.D.A., "Hyperhomocysteinemia, vascular pathology, and endothelial dysfunction", Seminars in Thrombosis and Hemostasis, 26, (2000), pp. 281-289.

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Publié-e

2004-12-01

Comment citer

HOUCHER, B., CANDITO, M., NECIB, S., NAIMI, D., & BEGAG, S. (2004). ASSESSMENT OF FOLATE STATUS: MEASUREMENT OF HOMOCYSTEINE versus VITAMIN B12 AND FOLATE. Sciences & Technologie. C, Biotechnologies, (22), 19–23. Consulté à l’adresse https://revue.umc.edu.dz/c/article/view/1362

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