EFFECTS OF Rosmarinus officinalis L. AQUEOUS EXTRACT ON ACUTE INFLAMMATION

Auteurs-es

  • Dalila Bouamra University Ferhat Abbas, Setif
  • Chekib-Arslane Baki University Ferhat Abbas, Setif
  • Abdelhamid Bouchebour University Ferhat Abbas, Setif
  • Saliha Dahamna University Ferhat Abbas, Setif
  • Hamama Bourriche University Ferhat Abbas, Setif
  • Samira Krache University Ferhat Abbas, Setif

Mots-clés :

Inflammation, anti-inflammatory activity, Rosmarinus officinalis L

Résumé

In this study, Rosmarinus officinalis L. aqueous extract was evaluated for anti-inflammatory activity by using the model of Carrageenan-induced rat paw oedema. Two doses of the aqueous extract (1500 mg/Kg and 3000 mg/Kg) were given orally by gavage technique, and then carrageenan was injected into the right hind paw of the rat. The extract, which was found rich in phenolic content (196.63 ± 3.09 mg GAE/ g E) and flavonoids (2.22 ± 0.09 mg RE/ g E), has shown a good inhibitory action (44.62 % in the third hour for the higher dose. *: p < 0.1) and close to that of aspirin that was used as a standard (31.87 % in the third hour for 200 mg/Kg aspirin.**: p < 0.05). The same effect was observed macroscopically on the gastric ulcer for both substances. However, the tissue alterations of the stomach were different at the histological study.

Bibliographies de l'auteur-e

Dalila Bouamra, University Ferhat Abbas, Setif

Laboratory of Chronic Diseases Applied Phytotherapy, , Faculty of Medicine

Chekib-Arslane Baki, University Ferhat Abbas, Setif

Laboratory of Chronic Diseases Applied Phytotherapy, , Faculty of Medicine

Abdelhamid Bouchebour, University Ferhat Abbas, Setif

Laboratory of Chronic Diseases Applied Phytotherapy, , Faculty of Medicine

Saliha Dahamna, University Ferhat Abbas, Setif

Laboratory of Chronic Diseases Applied Phytotherapy, , Faculty of Medicine

Hamama Bourriche, University Ferhat Abbas, Setif

Laboratory of Chronic Diseases Applied Phytotherapy, , Faculty of Medicine

Samira Krache, University Ferhat Abbas, Setif

Laboratory of Chronic Diseases Applied Phytotherapy, , Faculty of Medicine

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Publié-e

2015-12-01

Comment citer

Bouamra, D., Baki, C.-A., Bouchebour, A., Dahamna, S., Bourriche, H., & Krache, S. (2015). EFFECTS OF Rosmarinus officinalis L. AQUEOUS EXTRACT ON ACUTE INFLAMMATION. Sciences & Technologie. C, Biotechnologies, (42), 9–15. Consulté à l’adresse https://revue.umc.edu.dz/c/article/view/2031

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